Quarterback

Start:

Marcus Mariota (TEN): Mariota’s recent domination has propelled him into the top five quarterbacks in ESPN’s standard scoring. He has another great matchup this week as he squares off against the Colts’ porous defense.

Matthew Stafford (DET): Stafford has an excellent opportunity to have a strong return from his bye week, as he faces a poor Jaguars defense. Look for him to air it out and put up gaudy stats in the process.

Sit:

Carson Palmer (ARI): Palmer has an extremely daunting matchup in the Vikings, and with a couple of his top receivers banged up, there are better options at quarterback this week.

If you’re desperate:

Kirk Cousins (WAS): Cousins has been rolling after a dreadful start to the season and now faces a Green Bay secondary that does not match up well with the speed and physicality of Cousins’ receivers.

Running back

Start:

Robert Kelley (WAS): Kelley has operated as the Redskins’ clear No. 1 back, despite the fact that Matt Jones is healthy. He doesn’t have the best matchup in the Packers, but should see enough touches to have solid production.

Spencer Ware (KC): Ware has struggled recently, as he was recovering from a concussion. He has a great opportunity to get back on track against a Buccaneers defense that has a propensity to be torn apart by running backs.

Sit:

Jordan Howard (CHI): Howard has been successful as the Bears’ lead back, but has a tough matchup against the Giants, severely limiting his upside.

If you’re desperate:

C.J. Prosise (SEA): Prosise was Seattle’s workhorse last week, and that shouldn’t change with Christine Michael cut and Thomas Rawls returning from injury.

Wide receiver

Start:

Davante Adams (GB): Adams has been a target hog the past several weeks and Aaron Rodgers has increasingly trusted him as a result. He is now an every-week starter, especially against a thin Redskins secondary this week.

Julian Edelman (NE): With Rob Gronkowski’s status looking extremely doubtful, Edelman should see plenty of targets against a putrid 49ers defense. With Gronkowski out, Edelman is now Tom Brady’s top target. Look for him to have a big game.

Sit:

Jarvis Landry (MIA): Landry has been increasingly phased out of the Dolphins’ game plan with Jay Ajayi emerging as their top playmaker this season. In a run-first offense, he no longer has the upside needed to start him.

If you’re desperate:

Corey Coleman (CLE): Coleman is receiving steady targets, regardless of whom the Browns start at quarterback. He has a solid chance to get in the end zone this Sunday against a weak Steelers secondary.

Tight end

Zach Miller (CHI): Miller has been a favorite target of Jay Cutler, and with Alshon Jeffery suspended, he may be the best receiving option for Chicago. Volume alone should propel him to a good day against the Giants.

C.J. Fiedorowicz (HOU): Fiedorowicz has quietly produced solid numbers and gets another good chance to do some damage against a Raiders defense that has allowed the eighth most points per game to opposing tight ends.

Sit:

Zach Ertz (PHI): Ertz has been a steady contributor for the past couple of weeks, but now faces a daunting matchup in the Seahawks, making his floor extremely low.

If you’re desperate:

Ladarius Green (PIT): Green has the best matchup imaginable for a tight end this week as he faces the Browns. He was heavily involved on the field last week and an expected increase in targets should bode well for him this Sunday.