Lock:

San Diego (+1) over BUFFALO: San Diego’s offense looked great this weekend, and I don’t see that stopping. The Bills have a good defense, but not good enough to contain Chargers QB Phillip Rivers.

Dallas (-7) over ST. LOUIS: Tony Romo might start this game. But even if backup quarterback Brad Johnson has to go, the Cowboys will drive the Rams right into the ground.

Denver (+3) over NEW ENGLAND: Denver’s offense looks great, but their defense is suspect. The Patriots’ offense hasn’t been great this season, so I think that the Broncos will take this one.

Indianapolis (-1) over GREEN BAY: Joseph Addai is out this week, so Indy’s running game might stall a bit. But when you have Peyton Manning and good receivers, that’s not a big deal. Green Bay is good, but not good enough.